Publications


Sharif A, Baroncini M, Prevot V.
The Role of Glia in the Regulation of GnRH Neuronal Activity and Secretion.

Neuroendocrinology. 2013 May 28. [Epub ahead of print] PMID:21335953


Conductier G, Brau F, Viola A, Langlet F, Ramkumar N, Dehouck B, Lemaire T, Chapot R, Lucas L, Rovère C, Maitre P, Hosseiny S, Petit-Paitel A, Adamantidis A, Lakaye B, Risold PY, Prévot V, Meste O, Nahon JL, Guyon A.
Melanin-concentrating hormone regulates beat frequency of ependymal cilia and ventricular volume.
Nat Neurosci. 2013 May 26. doi: 10.1038/nn.3401.

 

Langlet F, Mullier A, Bouret SG, Prévot V, Dehouck B.
Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain.
J Comp Neurol. 2013 May 4. doi: 10.1002/cne.23355.

 

Langlet F, Levin BE, Luquet S, Mazzone M, Messina A, Dunn-Meynell AA, Balland E, Lacombe A, Mazur D, Carmeliet P, Bouret SG, Prevot V, Dehouck B.
Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting.
Cell Metab. 2013 Apr 2;17(4):607-17. doi: 10.1016/j.cmet.2013.03.004.

 

Bouret SG.
Organizational actions of metabolic hormones. Front
Neuroendocrinol. 2013 Jan;34(1):18-26. doi: 10.1016/j.yfrne.2013.01.001

 

Schaeffer M, Langlet F, Lafont C, Molino F, Hodson DJ, Roux T, Lamarque L, Verdié P, Bourrier E, Dehouck B, Banères JL, Martinez J, Méry PF, Marie J, Trinquet E, Fehrentz JA, Prévot V, Mollard P.
Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons.
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1512-7. doi:10.1073/pnas.1212137110.


Giacobini P, Prevot V.
Semaphorins in the development, homeostasis and disease of hormone systems.
Semin Cell Dev Biol. 2013 Mar;24(3):190-8. doi: 10.1016/j.semcdb.2012.11.005.

 

Parkash J, Cimino I, Ferraris N, Casoni F, Wray S, Cappy H, Prevot V, Giacobini P.
Suppression of
β1-integrin in gonadotropin-releasing hormone cells disrupts migration and axonal extension resulting in severe reproductive alterations.
J Neurosci. 2012 Nov 21;32(47):16992-7002. doi: 10.1523/JNEUROSCI.3057-12.2012.

 

Bouret SG.
RIPping off GABA release in hypothalamic circuits causes obesity.
Cell Metab. 2012 Nov 7;16(5):557-8. doi: 10.1016/j.cmet.2012.10.014.


Hanchate NK, Giacobini P, Lhuillier P, Parkash J, Espy C, Fouveaut C, Leroy C, Baron S, Campagne C, Vanacker C, Collier F, Cruaud C, Meyer V, García-Piñero A, Dewailly D, Cortet-Rudelli C, Gersak K, Metz C, Chabrier G, Pugeat M, Young J, Hardelin JP, Prevot V, Dodé C.
SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome.
PLoS Genet. 2012 Aug;8(8):e1002896. doi: 10.1371/journal.pgen.1002896.


Caron E, Ciofi P, Prevot V, Bouret SG.
Alteration in neonatal nutrition causes perturbations in hypothalamic neural circuits controlling reproductive function.
J Neurosci. 2012 Aug 15;32(33):11486-94. doi: 10.1523/JNEUROSCI.6074-11.2012.


Ishii Y, Bouret SG.
Embryonic birthdate of hypothalamic leptin-activated neurons in mice.

Endocrinology. 2012 Aug;153(8):3657-67. doi: 10.1210/en.2012-1328.


Batailler M, Mullier A, Sidibe A, Delagrange P, Prévot V, Jockers R, Migaud M.
Neuroanatomical distribution of the orphan GPR50 receptor in adult sheep and rodent brains.

J Neuroendocrinol. 2012 May;24(5):798-808. doi: 10.1111/j.1365-2826.2012.02274.x.


Coupé B, Ishii Y, Dietrich MO, Komatsu M, Horvath TL, Bouret SG.
Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation.
Cell Metab. 2012 Feb 8;15(2):247-55. doi: 10.1016/j.cmet.2011.12.016.


Bouret SG, Bates SH, Chen S, Myers MG Jr, Simerly RB.
Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits.
J Neurosci. 2012 Jan 25;32(4):1244-52. doi: 10.1523/JNEUROSCI.2277-11.2012.


Hanchate NK, Parkash J, Bellefontaine N, Mazur D, Colledge WH, d’Anglemont de Tassigny X, Prevot V.
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.
J Neurosci. 2012 Jan 18;32(3):932-45. doi: 10.1523/JNEUROSCI.4765-11.2012.


Baroncini M, Jissendi P, Balland E, Besson P, Pruvo JP, Francke JP, Dewailly D, Blond S, Prevot V.
MRI atlas of the human hypothalamus.
Neuroimage. 2012 Jan 2;59(1):168-80. doi: 10.1016/j.neuroimage.2011.07.013.


Messina A, Ferraris N, Wray S, Cagnoni G, Donohue DE, Casoni F, Kramer PR, Derijck AA, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P.
Dysregulation of Semaphorin7A/
β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility.
Hum Mol Genet. 2011 Dec 15;20(24):4759-74. doi: 10.1093/hmg/ddr403.


Clasadonte J, Poulain P, Hanchate NK, Corfas G, Ojeda SR, Prevot V.
Prostaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation.
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16104-9. doi: 10.1073/pnas.1107533108.


Bellefontaine N, Hanchate NK, Parkash J, Campagne C, de Seranno S, Clasadonte J, d’Anglemont de Tassigny X, Prevot V.
Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction.
Neuroendocrinology. 2011;93(2):74-89. doi: 10.1159/000324147.


Steculorum SM, Bouret SG.
Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring.
Endocrinology. 2011 Nov;152(11):4171-9. doi: 10.1210/en.2011-1279.


Prevot V, Hanchate NK, Bellefontaine N, Sharif A, Parkash J, Estrella C, Allet C, de Seranno S, Campagne C, de Tassigny Xd, Baroncini M.
Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions.
Front Neuroendocrinol. 2010 Jul;31(3):241-58. doi: 10.1016/j.yfrne.2010.05.003.


Prevot V, Bellefontaine N, Baroncini M, Sharif A, Hanchate NK, Parkash J, Campagne C, de Seranno S.
Gonadotrophin-releasing hormone nerve terminals, tanycytes and neurohaemal junction remodelling in the adult median eminence: functional consequences for reproduction and dynamic role of vascular endothelial cells.
J Neuroendocrinol. 2010 Jul;22(7):639-49. doi: 10.1111/j.1365-2826.2010.02033.x.


Duhem-Tonnelle V, Bièche I, Vacher S, Loyens A, Maurage CA, Collier F, Baroncini M, Blond S, Prevot V, Sharif A.
Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells.
J Neuropathol Exp Neurol. 2010 Jun;69(6):606-22. doi: 10.1097/NEN.0b013e3181e00579.


Parkash J, d’Anglemont de Tassigny X, Bellefontaine N, Campagne C, Mazure D, Buée-Scherrer V, Prevot V.
Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric oxide production during the ovarian cycle.
Endocrinology. 2010 Jun;151(6):2723-35. doi: 10.1210/en.2010-0007.


Sidibe A, Mullier A, Chen P, Baroncini M, Boutin JA, Delagrange P, Prevot V, Jockers R.
Expression of the orphan GPR50 protein in rodent and human dorsomedial hypothalamus, tanycytes and median eminence.
J Pineal Res. 2010 Apr;48(3):263-9. doi: 10.1111/j.1600-079X.2010.00750.x.


De Seranno S, d’Anglemont de Tassigny X, Estrella C, Loyens A, Kasparov S, Leroy D, Ojeda SR, Beauvillain JC, Prevot V.
Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence.
Endocrinology. 2010 Apr;151(4):1760-72. doi: 10.1210/en.2009-0870.


Mullier A, Bouret SG, Prevot V, Dehouck B.
Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain.
J Comp Neurol. 2010 Apr 1;518(7):943-62. doi: 10.1002/cne.22273.


Caron E, Sachot C, Prevot V, Bouret SG
Distribution of leptin-sensitive cells in the postnatal and adult mouse brain.
J Comp Neurol. 2010 Feb 15;518(4):459-76. doi: 10.1002/cne.22219.


Baroncini M, Jissendi P, Catteau-Jonard S, Dewailly D, Pruvo JP, Francke JP, Prevot V.
Sex steroid hormones-related structural plasticity in the human hypothalamus.
Neuroimage. 2010 Apr 1;50(2):428-33. doi: 10.1016/j.neuroimage.2009.11.074.

 

Ciofi P, Garret M, Lapirot O, Lafon P, Loyens A, Prévot V, Levine JE.
Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus.
Endocrinology. 2009 Dec;150(12):5509-19. doi: 10.1210/en.2009-0584.


Dufour C, Cadusseau J, Varlet P, Surena AL, de Faria GP, Dias-Morais A, Auger N, Léonard N, Daudigeos E, Dantas-Barbosa C, Grill J, Lazar V, Dessen P, Vassal G, Prevot V, Sharif A, Chneiweiss H, Junier MP.
Astrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation.
Stem Cells. 2009 Oct;27(10):2373-82. doi: 10.1002/stem.155.

 

D’Anglemont de Tassigny X, Campagne C, Steculorum S, Prevot V.
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures.
J Neurochem. 2009 Apr;109(1):214-24. doi: 10.1111/j.1471-4159.2009.05949.x.


Patterson CM, Bouret SG, Dunn-Meynell AA, Levin BE.
Three weeks of postweaning exercise in DIO rats produces prolonged increases in central leptin sensitivity and signaling.
Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R537-48. doi: 10.1152/ajpregu.90859.2008.


Sharif A, Duhem-Tonnelle V, Allet C, Baroncini M, Loyens A, Kerr-Conte J, Collier F, Blond S, Ojeda SR, Junier MP, Prevot V.
Differential erbB signaling in astrocytes from the cerebral cortex and the hypothalamus of the human brain.
Glia. 2009 Mar;57(4):362-79. doi: 10.1002/glia.20762.


Bouret SG, Gorski JN, Patterson CM, Chen S, Levin BE, Simerly RB.
Hypothalamic neural projections are permanently disrupted in diet-induced obese rats.
Cell Metab. 2008 Feb;7(2):179-85. doi: 10.1016/j.cmet.2007.12.001.

 

Clasadonte J, Poulain P, Beauvillain JC, Prevot V.
Activation of neuronal nitric oxide release inhibits spontaneous firing in adult gonadotropin-releasing hormone neurons: a possible local synchronizing signal.
Endocrinology. 2008 Feb;149(2):587-96.


Baroncini M, Allet C, Leroy D, Beauvillain JC, Francke JP, Prevot V.
Morphological evidence for direct interaction between gonadotrophin-releasing hormone neurones and astroglial cells in the human hypothalamus.
J Neuroendocrinol. 2007 Sep;19(9):691-702.


D’Anglemont de Tassigny X, Campagne C, Dehouck B, Leroy D, Holstein GR, Beauvillain JC, Buée-Scherrer V, Prevot V.
Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of adult female reproduction.
J Neurosci. 2007 Jun 6;27(23):6103-14.


Sharif A, Legendre P, Prévot V, Allet C, Romao L, Studler JM, Chneiweiss H, Junier MP.
Transforming growth factor alpha promotes sequential conversion of mature astrocytes into neural progenitors and stem cells.
Oncogene. 2007 Apr 26;26(19):2695-706.